Pulmonary talcosis caused by intravenous methadone injection

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Pulmonary talcosis caused by intravenous methadone injection

A 38-year-old woman presented to our pulmonology clinic with complaints of progressive dyspnea and dry cough for more than three months. She denied fever or weight loss. On physical examination, she presented as hypoxemic, with a room air oxygen saturation of 92% and an RR of 24 breaths/min. Pulmonary function tests showed that spirometric values were within normal limits, but there was a sligh...

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Pulmonary talcosis with intravenous drug abuse.

Talc has been known to cause lung disease, via inhalation or intravenously. A good history along with radiological correlation will often reveal the diagnosis. However, most intravenous drug abusers are reluctant to give a history of exposure, and most diagnoses are made after lung biopsy. We present a case of acute respiratory failure that posed a diagnostic challenge and was diagnosed only af...

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Remifentanil Prevents Withdrawal Movements Caused by Intravenous Injection of Rocuronium

PURPOSE The incidence of pain induced withdrawal movement following intravenous injection of rocuronium is high. This randomized, double-blind, placebo-controlled study was designed to evaluate the effect of pretreatment of remifentanil on the withdrawal movements due to intravenous injection of rocuronium during anesthetic induction. MATERIALS AND METHODS Ninety adult female patients undergo...

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Intravascular Talcosis due to Intravenous Drug Use Is an Underrecognized Cause of Pulmonary Hypertension

Intravenous injection of illegal drugs or medications meant for oral administration can cause granulomatous disease of the lung. This intravascular talcosis results in pulmonary fibrosis and pulmonary hypertension. Nine cases of histologically confirmed intravascular talcosis were reviewed with specific attention given to the clinical histories in these patients. Five autopsy cases were include...

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Acute Pulmonary Vascular Talcosis: Mimicking Acute Pulmonary Embolism

Intravenous injection of powdered tablets intended to oral use is a common practice among drug abusers, given the greater effectiveness attributed to accelerate delivery of the drug through this route compared to oral intake. This can result in both acute and chronic changes in the pulmonary vessels and parenchyma. Various terms have been used to describe this entity and include self-induced pu...

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ژورنال

عنوان ژورنال: Jornal Brasileiro de Pneumologia

سال: 2017

ISSN: 1806-3713

DOI: 10.1590/s1806-37562016000000337